New era of personalised epilepsy management

Z Chen; B Rollo; A Antonic-Baker; A Anderson; Y Ma; TJ O'Brien; Z Ge; X Wang; P Kwan

Journal article

New era of personalised epilepsy management

Z Chen, B Rollo, A Antonic-Baker, A Anderson, Y Ma, TJ O'Brien, Z Ge, X Wang, P Kwan

BMJ | BMJ PUBLISHING GROUP | Published : 2020

DOI: 10.1136/bmj.m3658

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Abstract

The trial and error approach to epilepsy treatment has not changed for over a century but machine learning and patient derived stem cells promise a personalised and more effective strategy, argue Patrick Kwan and colleagues

University of Melbourne Researchers

Alison Anderson Author

Patrick Kwan Author

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HUMAN EPILEPSY: UNDERSTANDING BIOLOGY TO IMPROVE OUTCOMES

Our team of neurologists, molecular geneticists, physiologists and brain imaging specialists and leads the world in the discovery of the gen..

Grants

Awarded by Royal Melbourne Hospital Neuroscience Foundation

Funding Acknowledgements

We have read and understood BMJ policy on declaration of interests and have the following interests to declare: ZC is supported by an early career fellowship from the National Health and Medical Research Council (NHMRC) of Australia (GNT1156444). PK is supported by a Medical Research Future Fund (MRFF) from the NHMRC of Australia (MRF1136427). PK and BR are supported by a MRFF Stem Cell Therapies grant (APP1201781). His institution has received speaker or consultancy fees and/or research grants from Biscayne, Eisai, GW Pharmaceuticals, LivaNova, Novartis, UCB Pharma and Zynerba. TOB is supported by a programme grant from the NHMRC of Australia (APP1091593), and the Royal Melbourne Hospital Neuroscience Foundation. AAB, AA, YM, ZG, and XW report no conflicts of interest.